AFP: American Family Physician Podcast Episode 237 -- September 2025 -- Part 1 AFP: American Family Physician
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Sep 15, 2025 Discover the latest on respiratory syncytial virus vaccination in pregnancy, showcasing its success in reducing infant hospitalizations. Learn about vasectomy techniques that minimize complications and recovery. Dive into donanemab, a breakthrough treatment for Alzheimer’s, while weighing financial hurdles. Explore innovative cancer detection methods and the pressing need for early autism screening in primary care. Finally, unravel a new risk scoring system for diagnosing acute pancreatitis, enhancing diagnostic accuracy.
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Maternal RSV Vaccination Lowers Infant Hospitalization
- Maternal RSV vaccination given in late pregnancy reduces infant RSV hospitalizations with high-certainty evidence.
- CDC and major organizations recommend seasonal vaccination between 32+0 and 36+6 weeks during RSV season.
Technique And Follow-Up For Safer Vasectomy
- Use the no-scalpel technique and fascial interposition to reduce complications and recanalization in vasectomy.
- Confirm sterility with semen analysis after ~3 months and ~20 ejaculations while advising interim contraception.
Donanemab: Plaque Removal With Limited Clinical Gain
- Donanemab reduces amyloid plaques but produces only small, clinically questionable slowing of cognitive decline in early Alzheimer's.
- Treatment has substantial MRI monitoring needs and notable risk of amyloid-related imaging abnormalities.