AFP: American Family Physician Podcast

A rapid tour of practical primary care updates: spotting spondyloarthropathies, choosing inhaled corticosteroid doses for asthma flares, and treating opioid use disorder. The discussion also covers foodborne illness management, emerging oral therapy for gonorrhea, and evidence supporting seven days rather than 14 for uncomplicated gram-negative bacteremia.

This clinical roundup explores quitting smokeless tobacco, distinguishing routine ear pain from warning signs, and weighing testosterone therapy’s benefits and risks. It also covers cognitive behavioral therapy, RSV vaccine protection for older adults and infants, and evidence-based ADHD treatments across age groups.

PCSK9 inhibitors (1:50), treatment of opiate use disorder (4:20), healthy dietary advice (6:20), the top 20 research studies of 2025 (11:40), atopic dermatitis prevention (15:10), and ambient temperature increase impact on pregnancy outcomes (17:10). Please fill out our listener survey!

Telemedicine for medical abortion and its safety up to 12 weeks. Updated approaches to diagnosing and managing Crohn's disease. Recognition and treatment strategies for shingles and post-herpetic neuralgia. Health concerns linked to ultra-processed foods and dietary alternatives. Evidence supporting high-dose flu vaccine for older adults. New recommendations for evaluating microhematuria.

A rapid tour of urgent eye complaints and red flags to watch for. A look at steroids in sepsis and the evidence around mortality. Discussion of a new drug for motion sickness and its tradeoffs. Examination of risk-based mammography using genetic stratification. Exploration of menopause links to fatty liver risk. Practical steps for climate-smart health care.

They preview World Cup–related clinical presentations and coding to watch for. They define and work through evaluation and targeted testing for amenorrhea. They discuss wrist acupuncture for postoperative nausea and vomiting. They review limited evidence for medications for cannabis use disorder. They cover knee pain assessment and a bathing trial for eczema.

They cover nausea and vomiting in pregnancy, including assessment and multi-step treatments. They review desmopressin for bedwetting and debate universal lipid screening in children. Recurrent urinary tract infections are discussed from diagnosis to prevention. They examine oral decongestants and blood pressure, and introduce the new LumiPulse blood test for Alzheimer disease.

Practical guidance on starting and titrating basal insulin for type 2 diabetes, avoiding over‑basalization, and when to add mealtime insulin. Discussion of PrEP use trends and its role in HIV prevention. Evidence that CPAP lowers 24‑hour blood pressure in obstructive sleep apnea. Overview of metabolic dysfunction‑associated steatotic liver disease screening, lifestyle and medication options, and concerns about overscreening. Clinical scoring for appendicitis.

Postoperative care and nutrient monitoring after metabolic and bariatric surgery, including long-term follow up. Risks and counselling points for e-cigarette use and respiratory health. New guidance on outcome-focused type 2 diabetes treatments and individualized A1C goals. HIV screening, rapid antiretroviral start, PrEP/PEP access, and preventive care. Strategies and evidence for preventing falls and using NSAIDs for renal colic.

Conversations cover severe hypertension definitions, evaluation, and cautious blood pressure management. They discuss extended low‑dose anticoagulation after provoked venous clots and pivmecillinam as an option for acute cystitis. Practical approaches to skin and soft tissue infections, including abscess care and preventing recurrence, are reviewed. Testing strategies for community‑acquired fungal pneumonias are also outlined.