The Internet Book of Critical Care Podcast

IBCC Episode 21 - Antibiotics

21 snips
Jan 27, 2019
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ADVICE

Antibiotic Initiation

  • Avoid blindly starting antibiotics unless the patient has septic shock or neutropenic fever.
  • Differentiate colonization from infection, especially in tracheal cultures, as they may not require treatment.
ADVICE

Antibiotic Modification

  • Start with empiric therapy and send off microbiologic studies.
  • Re-evaluate within 24-48 hours and narrow antibiotics based on culture results, shifting to definitive therapy ideally.
INSIGHT

Treatment Failure

  • Treatment failure can stem from various factors, not just antibiotic resistance.
  • Consider underdosing, abscesses, or even the absence of a true infection.
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