Why You Still Feel Sick: The Mystery of Histamines, Long COVID & POTS

Oct 14, 2025

49:35

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Integrative and functional dietitian Michelle Shapiro joins Don Saladino for a conversation about living in a highly sensitive body, and what happens when your nervous system, gut, and immune system are all turned up to eleven.

Michelle breaks down the connection between histamine intolerance, gut health, and anxiety, explaining why some people are naturally more reactive to foods, environments, or even stress. She and Don explore how histamine issues often go misdiagnosed, how nervous system regulation impacts digestion and inflammation, and what recovery looks like for people who feel “wired and tired” all the time.

They also tackle the emotional side of healing, the frustration of doing everything “right” and still feeling off, and share realistic steps to calm the body, balance the mind, and rebuild trust in your system.

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