A brand-new colour created by lasers, a pig-liver transplant trial gets the green light, and a nugget-sized chunk of lab-grown meat
Apr 23, 2025
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In this lively discussion, science journalists Lizzie Gibney and Sharmini Bandel dive into the creation of a brand-new color called ‘olo,’ visible only to a select few, highlighting how laser technology can enhance our understanding of color perception and aid those with color blindness. They also unpack the FDA's approval for a groundbreaking pig-liver transplant trial, aiming to address organ failure with genetically modified livers. Finally, they explore an impressive lab-grown meat development, discussing its potential to revolutionize food production.
A groundbreaking discovery of a new color, visible only under experimental conditions, could enhance our understanding of human color perception and assist colorblind individuals in the future.
The FDA's approval for a pig-liver transplant trial marks a significant step forward in xenotransplantation, potentially addressing organ shortages and enhancing treatment options for patients with liver failure.
Deep dives
The Discovery of a New Color
A new color, described as a saturated bluey-green, has been identified, but it can only be seen under specific experimental conditions by a limited number of participants. This discovery illustrates the complexity of human color perception, as color interpretation involves multiple light receptor cells in the eye called cones, which transmit varying signals to the brain. Researchers used advanced technology to isolate signals from the cones that correspond to this unique shade, allowing participants to 'see' a color that had never been experienced before. The implications of this research extend beyond curiosity, as it may pave the way for practical applications such as helping colorblind individuals regain a fuller perception of color through targeted stimulation of their cone cells.
Advancements in Xenotransplantation
Xenotransplantation, specifically the use of pig livers for patients with liver failure, has progressed significantly with a recent FDA approval for clinical trials. This trial will involve using pig livers externally to filter the blood of patients with a critical form of liver disease, providing a lifeline for individuals who cannot receive human liver transplants. Preliminary experiments have shown promise, including previous cases where pig organs have been used in clinically dead patients, leading to vital insights into organ compatibility and rejection mechanisms. The research aims to refine genetic modifications of pigs to create organs that can be successfully transplanted into humans, addressing the dire shortage of human organs.
Innovations in Lab-Grown Meat Production
A breakthrough has been made in lab-grown meat, particularly with the successful cultivation of a small, chicken-like meat chunk using an innovative method that mimics blood vessel functions. By utilizing semi-permeable hollow fibers similar to those in kidney dialysis machines, researchers can supply the required oxygen and nutrients to muscle cells, enabling them to grow into a larger structure akin to a chicken nugget. This advancement addresses a significant challenge in producing lab-grown meat, which typically involved smaller pieces due to the complexities of nutrient delivery. Although there are hurdles to overcome, including texture enhancement and scalability, this research holds potential not only for food sustainability but also for applications in regenerative medicine.
Using a laser system to activate specific eye cells, a team has allowed five study participants to perceive a vibrant blue-greenish hue well outside the natural range of colours seen by humans. Although the setup required to accomplish this feat is currently complicated, this finding could provide more understanding about how the brain perceives colour and could one day help boost the vision of people with colour blindness.
08:30 US regulator greenlights pig-liver transplant trial
The US Food and Drug Administration has approved the first trial to test whether genetically modified pig livers can be used safely to treat people with organ failure. In the initial phase of the trial, four people with severe liver failure will be temporarily connected to an external pig liver that will filter their blood. Participants will then be monitored for a year for safety and changes in liver function. The organs have been genetically modified to make them more compatible with humans.
Using a designer ‘circulatory system’, a team of researchers have created what they think is the largest piece of meat grown in the laboratory yet. One of the challenges to producing larger pieces of lab-grown meat has been providing cells with sufficient oxygen and nutrients, something the team’s new setup helps overcome. They used it to grow a chunk of chicken muscle about the size of a nugget, but multiple challenges remain before meat produced in this way could make it to market.