The Stem Cell Podcast
Ep. 277: “Lung Development” Featuring Dr. Behzad Yeganeh
Oct 1, 2024
Dr. Behzad Yeganeh, an Associate Scientist at the Children’s Hospital of Eastern Ontario, dives into the complexities of lung development and neonatal lung diseases. He shares fascinating insights into the mechanisms of autophagy and apoptosis, vital for understanding lung health. The conversation spans the challenges of premature lung disease and innovative approaches such as using mesenchymal stem cells for therapy. Yeganeh's journey from cancer biology to regenerative medicine reveals a promising path for improving neonatal care.
01:14:44
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Quick takeaways
- Understanding the mechanisms of lung development is essential for improving therapeutic strategies for neonatal lung diseases, especially in premature infants.
- Chemically induced pluripotent stem cells (iPSCs) have shown promising results in treating type 1 diabetes, indicating their potential for future therapies.
Deep dives
Mechanisms of Lung Development and Neonatal Lung Diseases
Research into the mechanisms of lung development and neonatal lung diseases is vital for improving outcomes for premature infants. The speaker highlights how the intricacies of lung physiology, particularly in the alveolar regions, impact therapeutic strategies., especially considering the significant challenges posed by conditions like bronchopulmonary dysplasia. Understanding these mechanisms can help identify better therapeutic strategies to mitigate lung injury in neonates. Current approaches include utilizing mesenchymal stem cells for potential applications in treating early lung injury caused by interventions such as mechanical ventilation.
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