#53 - Alejandro Junger: Ibogaine, Neuroplasticity, and Gut Health

Nov 26, 2025

Ask episode

Chapters

Transcript

Episode notes

What happens when one of the world’s leading voices on detoxification and the gut brain connection experiences Ibogaine? On this episode, Talia Eisenberg sits down with Dr. Alejandro Junger to explore the scientific mechanisms behind Ibogaine and its potential to reset the entire nervous system.

Dr. Junger explains how Ibogaine interacts with neurotransmitters, neuroplasticity, and the enteric nervous system. He describes why the gut contains more neurons than the brain in the skull, how noribogaine may influence inflammation and mood, and why repairing the intestinal wall is central to long term mental health. The conversation focuses on the biology of depression, the critical role of the microbiome, and the risks and safety protocols around Ibogaine. Dr. Junger also shares how Ibogaine shifted his own depressive physiology.

Dr. Alejandro Junger is a triple board certified physician in internal medicine, cardiology, and functional medicine. He is the bestselling author of Clean, Clean Gut, Clean Eats, and Clean Seven.

Links

Timestamps

(00:00); Intro, Alejandro’s background and visit to Beond
(10:00); Divorce, survival mode, anger and the slide into depression
(16:00); Early Ibogaine work in Mexico and his first non visionary Ibogaine session
(21:00); Avoiding antidepressants, choosing Ibogaine, and the intention to forgive
(25:00); Open heart surgery, cardiac risk, and ibogaine vs noribogaine explanation
(30:00); Supplemental dose, sudden emotional shift, and relief of depressive heaviness
(35:00); Three brains model – head, gut, heart and the gut as an intuitive brain
(41:00); Leaky gut, microbiome, chronic inflammation and modern chronic disease
(48:00); Ibogaine for personal growth vs crisis and witnessing veteran transformations at Beond
(58:00); Combining Clean gut repair protocols with Ibogaine before, during, and after treatment
(01:10:00); Future of centers, human connection, and where to find Dr. Junger’s work