The Four Hormones Most Adults Need More Of - Discussion between Georgi Dinkov and Dr. Mercola
Dec 6, 2023
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Dr. Mercola and Georgi Dinkov discuss hormone supplementation and the importance of progesterone, T3, DHEA, and pregnenolone. They explore the role of hormones in overall health, aging, and cancer risk. They also touch on analyzing diet and nutrient intake, the molecular mechanisms of calcium, estrogen, and linoleic acid, maximizing hormone absorbability with fatty acids, and the benefits of dissolving progesterone in vitamin E. They further discuss the benefits and optimal dosage of progesterone for women.
Progesterone is a crucial hormone with pro-thyroid and thermogenic effects, protecting against cortisol excess and inhibiting enzyme synthesis of cortisol.
Transdermal progesterone should be avoided as it converts to alopregnanolone, resulting in less progesterone available in its original form.
Moringa oil is a healthier alternative to oils high in polyunsaturated fats, while choosing the right form of vitamin E is crucial for optimal health.
Deep dives
Progesterone: Benefits and Dosage
Progesterone is a crucial hormone that can provide various benefits to the body. It has pro-tyroid and thermogenic effects, raising the metabolic rate by about 10%. When taken orally with proper oils and vitamin E, it has a positive impact on producing more progesterone. Progesterone also acts as an aromatase inhibitor and antagonizes estrogen receptors. It helps protect against cortisol excess and inhibits the enzyme 11 beta HSD1, which synthesizes cortisol. The recommended dose for pre-menopausal women is typically 25-50 milligrams, but it's crucial to be mindful of timing to avoid hormonal imbalances.
The Importance of Avoiding Transdermal Progesterone
It's important to avoid using transdermal progesterone as the skin has a high expression of 5-alpha reductase enzyme, which converts progesterone to alopregnanolone. This conversion cannot be reversed and results in less progesterone available in its original form. Alopregnanolone has its effects but should not be the primary focus if the goal is to benefit from progesterone. By taking progesterone orally with the proper oils, more progesterone remains unmetabolized and provides its full range of benefits.
Promoting Optimal Health with Progesterone
Progesterone plays a significant role in promoting optimal health. It has anti-glucocorticoid effects, meaning it antagonizes the effects of cortisol, and also inhibits the release of adrenaline. By taking progesterone, individuals can combat the HPA overactivity syndrome that is prevalent in today's society. Additionally, progesterone acts as an aromatase inhibitor, prevents estrogen conversion, and blocks estrogen receptors. It also has thermogenic and pro-tyroid effects, raising the metabolic rate and promoting fat metabolism. Overall, progesterone is a crucial hormone for maintaining hormonal balance and overall wellness.
Using Moringa Oil as an Alternative to Olive Oil
Moringa oil is similar to unfiltered olive oil in terms of its health benefits due to its phenolic compounds. It can be a better version of olive oil, especially for those concerned about health. Moringa oil has a low percentage of polyunsaturated fats, making it a healthier choice than oils high in these fats. It is important to ensure that the moringa oil is not adulterated.
The Importance of Vitamin E and Choosing the Right Form
Vitamin E is essential for optimal health and has benefits like being an antioxidant, anti-estrogen, and anti-inflammatory. However, it is crucial to choose the right form of vitamin E, free from synthetic versions and esters like acetate. The ideal vitamin E supplement should contain mixed non-esterified D isomers, including alpha, beta, gamma, and delta-tocopherols. Consuming around 2 milligrams per gram of linoleic acid intake is recommended, but it's important to avoid vitamin E supplements with a fishy smell, indicating rancidity.