Finding and backing companies that can reach escape velocity is the name of the game over here at a16z Growth—but picking those winners is far from easy. David George, head of the a16z Growth fund, sat down with the I/O podcast to discuss his mental models for growth-stage investing, what it really takes to go public, where AI is today and where it’s headed, and more. 

[00:03:19] What makes Andreessen Horowitz different

[00:08:29] David's mental model for investing

[00:18:23] Focusing on inputs, not outputs

[00:26:52] What constitutes a growth company?

[00:29:14] David's three investing frameworks

[00:36:45] How to measure the ROI of R&D

[00:42:15] What it takes to go public today

[00:46:43] AI: market structure and infrastructure vs. application layers

To read a transcript of this conversation, click here.