In this episode, Sanjay speaks to David Putrino, the director of rehabilitation innovation for the Mount Sinai Health System. They discuss the impact of long COVID on the brain, ongoing research in identifying biomarkers for the condition, the risks associated with long COVID, and the importance of inclusion and funding for research. They also highlight the importance of maintaining hope while being honest with long-COVID patients.
Long Covid patients may experience symptoms such as extreme fatigue, cognitive difficulties, memory loss, breathlessness, and autonomic dysfunctions.
The understanding and treatment of Long Covid are still evolving, highlighting the need for personalized approaches in diagnosis and treatment.
Deep dives
Long COVID: A Mysterious Phenomenon with Lasting Impact
Long COVID, a term used to describe persistent symptoms in individuals who have recovered from COVID-19, has emerged as a significant and diverse health concern. Many patients experience symptoms such as extreme fatigue, cognitive difficulties, memory loss, breathlessness, and even autonomic dysfunctions like Postural Orthostatic Tachycardia Syndrome (POTS). Researchers have been studying the impact of long COVID on the brain and have found changes in brain size, cognitive function, and chemical imbalances. Additionally, the virus can cause damage to blood vessels, leading to microclots. Identifying long COVID has proven challenging, as it presents differently in each individual, highlighting the need for personalized approaches in diagnosis and treatment. While the understanding and treatment of long COVID are still evolving, experts recommend factoring it into the risk equation, taking precautions, and seeking medical support for managing symptoms.
The Complex Journey of Understanding Long COVID
Long COVID poses numerous challenges for researchers, healthcare providers, and patients alike. The condition is not well understood, and there is no definitive biomarker for diagnosis. Neuronal changes in the brain have been observed, both during acute COVID infection and in long COVID cases. Inflammation and chemical imbalances contribute to neural damage, affecting cognitive function and causing symptoms like brain fog. Patients with long COVID often experience dysautonomia and POTS, which can further disrupt their quality of life. Research is ongoing to identify biomarkers and refine diagnostic criteria. The development of effective treatments for long COVID is essential, given its significant and varied impact on individuals.
Addressing the Impact of Long COVID on Daily Life
Long COVID has profound implications for individuals' daily lives, affecting their ability to work, engage in social activities, and experience normalcy. The symptoms of long COVID can be debilitating, with extreme fatigue, physical limitations, emotional lability, and memory impairments often reported. There is a need for a better understanding of the condition's impact and comprehensive support systems. Long COVID clinics and patient-led communities provide valuable resources and platforms for sharing experiences, insights, and treatment options. By acknowledging the challenges faced by long COVID patients and promoting awareness, society can foster empathy, inclusion, and support for individuals navigating this complex and chronic condition.
Navigating the Uncertainties of Long COVID
The uncertainties surrounding long COVID make it crucial for individuals experiencing persistent symptoms to seek appropriate medical attention and advocate for themselves. Accessing specialized long COVID clinics and healthcare professionals experienced in the condition can provide valuable guidance in diagnosis and treatment. While no definitive cure or universal treatment exists, there are interventions available that can alleviate some symptoms and improve quality of life. Research and clinical trials are ongoing, aiming to identify effective treatments and validate personalized approaches for managing long COVID. With continued focus and collaborative efforts, progress can be made in understanding, addressing, and finding solutions for the challenges posed by long COVID.
More than three years after the outset of the Covid-19 pandemic, many long Covid patients are still experiencing brain fog, extreme fatigue, and myriad other health issues, leaving some unable to complete even the most basic of daily tasks. How should long Covid patients approach treatment, let alone everyday life? In this episode, Sanjay speaks to David Putrino, the director of rehabilitation innovation for the Mount Sinai Health System. He tells us about his latest research into identifying a possible biomarker for the condition and how we can all help those at high risk of developing it.