

S5 EP3: Bryan Johnson discusses life-changing psychedelics, superintelligence, and night-time erections
May 19, 2025
Bryan Johnson, a tech entrepreneur and longevity advocate, dives deep into his quest for eternal life and the role of psychedelics in his transformation. He discusses how radical lifestyle changes and biohacking practices may slow aging. The conversation meanders through the philosophical implications of seeking immortality, balancing self-discipline with indulgence, and the emerging concept of superintelligence. Additionally, he shares intriguing insights on health, wellness, and the impact of technology on our lives, all punctuated by a light-hearted exploration of night-time erections.
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Decade-Long Depression Anecdote
- Bryan Johnson once struggled with depression for a decade while building a billion-dollar company.
- Despite his low mood, he raised three kids and kept functioning during this period.
Fire Your Willpower Self
- Fire your low-willpower self from making bad decisions during high-risk times.
- Write down arguments to counter urges and avoid relying on willpower when vulnerable.
Origin of "Blood Boy" Term
- The term "blood boy" originated from an HBO series parodying eccentric executives.
- Bryan Johnson embraced this nickname after media attention on his plasma infusions from his son.