The Top Line cover image

The Top Line

Bridging the gap from clinical trials to real-life HIV care (Sponsored)

Mar 10, 2025
Dr. Luis Buzón, an infectious disease specialist and spokesman for the Spanish Society of Infectious Diseases, sheds light on the vital role of real-world evidence in HIV care. He emphasizes how long-term data reveal treatment effectiveness and side effects often missed in clinical trials. Buzón shares a personal connection to HIV advocacy, inspired by his father's pioneering work in Spain. The discussion highlights the importance of inclusive research to improve health outcomes and the ongoing journey towards compassionate, evidence-based care.
16:26

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Real-world evidence is essential for understanding long-term effects and safety of HIV treatments beyond the short-term focus of clinical trials.
  • The underrepresentation of certain demographics in clinical trials highlights the importance of real-world data to guide effective treatment for all patients.

Deep dives

The Importance of Real-World Evidence in HIV Treatment

Real-world evidence plays a crucial role in understanding HIV treatment and prevention by providing data from patients in everyday life after a drug has been approved. Clinical trials often focus on effectiveness over shorter timeframes, which may not capture the long-term side effects that can emerge over years of medication use. For instance, some drugs that initially appear beneficial can reveal significant toxicities after long-term use, necessitating ongoing research outside of controlled trials. Collecting data on patient experiences helps inform better treatment decisions and highlights the importance of monitoring drug performance post-commercialization.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode