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In this episode, Dr. Mohammed Hagahmed, a faculty physician at the University of Pittsburgh Medical Center, shares a compelling case of a patient named Miss Z, a recent immigrant with COPD. Dr. Hagahmed discusses the challenges of caring for crashing patients, focusing on the critical importance of peri-intubation resuscitation. He delves into factors that can lead to peri-intubation cardiac arrest, such as hypoxemia, hypotension, and high shock index. He also discusses the choice of sedation and paralytic agents, emphasizing the need to ensure appropriate sedation when intubating patients. Dr. Hagahmed provides valuable insights into managing these high-risk scenarios and the latest research findings on the topic.