Huberman Lab

Essentials: Erasing Fears & Traumas Using Modern Neuroscience

867 snips
Nov 6, 2025
Explore the fascinating neuroscience behind fear and trauma. Discover how the amygdala and prefrontal cortex play crucial roles in processing fear. Learn why it’s vital to replace old fears with new positive associations, not just extinguish them. Delve into effective therapies like prolonged exposure and cognitive behavioral therapy that use detailed recounting to lessen traumatic responses. Uncover the impact of social connections on healing and innovative treatments, including ketamine and MDMA. Plus, find out how a brief daily stress protocol can help rewire fear responses!
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Fear Is More Than Just Stress

  • Fear is an emotion built from stress, autonomic arousal, and cognitive components like memory and meaning.
  • Trauma occurs when fear becomes maladaptively embedded and reactivates at inappropriate times.
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Autonomic Balance Underlies Fear Responses

  • The autonomic nervous system balances sympathetic (alerting) and parasympathetic (calming) states that underlie fear.
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Amygdala Links Threat To Reward Systems

  • The amygdala integrates sensory and memory input to trigger the threat reflex and drives outputs to arousal and reward systems.
  • Amygdala projections to dopamine pathways explain how fear memories can be reinforced or remapped.
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