Bloody Minded Episode 2 - In the Lab: PT and aPTT
May 21, 2024
Explore the real-life challenges of blood sample collection and its implications in coagulation testing. Discover the critical importance of filling the coagulation tube properly—especially during those late-night shifts. Delve into the intricate processes behind prothrombin time (PT) and activated partial thromboplastin time (APTT) tests and the hurdles clinical teams face. Understand how platelets play a vital role in clotting and why accurate assessments are essential for patient care. Get ready to feel a bit guilty about underfilled tubes!
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JMO Underfilled Blue Tube Anecdote
- A night intern underfilled a blue top coagulation tube during a difficult shift and the lab rejected the sample.
- This common mistake can lead to delays and frustration in urgent coagulation testing scenarios.
Coagulation Tests vs Bleeding Time
- Coagulation tests measure blood's ability to clot outside the body, not real-time hemostasis.
- The old bleeding time test involved cutting skin and timing blood loss, but was painful and impractical.
Always Fill Blue Coag Tubes
- Always fill coagulation (blue top) tubes completely to ensure ratio of blood to anticoagulant is correct.
- Underfilling causes excess anticoagulant and falsely prolonged clotting times, making results unreliable.