ACR Journals On Air cover image

ACR Journals On Air

B-Cells in Sjogren's Syndrome

Mar 5, 2024
Dr. Steinmetz discusses B cell hyperactivity in Sjogren's Syndrome, ASC maturity, salivary gland infiltration, and new technologies in antibody cell analysis. The podcast also explores the challenges in studying IgG levels, international research experiences, and the evolving nature of scientific knowledge.
35:32

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • B cell maturity in Sjogren's Syndrome is crucial due to elevated autoantibodies and infiltration in affected tissues.
  • A maturity index combining multiple markers can serve as a potential biomarker for disease activity assessment in Sjogren's Syndrome.

Deep dives

Importance of Studying B Cell Maturity in Shogren's Syndrome

Studying B cell maturity in Shogren's Syndrome is crucial due to the prominence of B cells in the disease. Patients often exhibit elevated autoantibodies and altered B cell subsets. B cells can infiltrate affected tissues, forming antibody secreting cells and lymphoepithelial lesions. High dimensional spectral flow cytometry helps analyze markers of B cell maturity.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode