TGM Classic | Giles Yeo | From Calorie Counting to Quality Eating: A Holistic Approach to Wellness

Jul 7, 2025

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What if calories aren’t the whole story?

In the realm of nutrition and health, the traditional belief has been that counting calories is the ultimate key to managing one’s diet effectively. But what if we told you calories might not be the key to a healthy diet? Delving beyond the calorie count, this question encourages us to explore the multifaceted elements that influence our health and well-being, such as food quality, nutrient content, and individual genetic factors.

Giles Yeo, a biologist and professor of molecular neuroendocrinology at the Medical Research Council Metabolic Diseases Unit, and scientific director of the Genomics/Transcriptomics Core at the University of Cambridge, challenges the conventional wisdom surrounding weight management.

In this episode of The Greatness Machine, Darius is joined by Giles to shed light on the importance of food quality, nutrient partitioning, and the role of genetics in our individual responses to diet and exercise. His perspective invites us to reevaluate our approach to nutrition, weight loss, considering a more holistic view of health that goes beyond calorie counting.

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