“I realize there's this massive disconnect in the business model whereby you've got governments and health insurers paying billions and billions of dollars for what might be a not very effective therapy, and then there's all these potential cures, even, and much better treatments out there.” - Savva Kerdemelidis Savva Kerdemelidis and Zan Lowe, of Public Good Pharma, joined me this week to talk about re-aligning the incentive structures for drug development.  In our current system, drugs are often funded based on how much of their formula is patentable, and manufacturers will tweak the formulas in order to get new patents when they’ve run out. So how do we fix the system, for the public good?  Savva’s solution is to “self-fund” pharmaceutical trials, through employers. These trials can be used to determine if lower cost drugs have the same or better effect than more expensive, patented ones (which they often do), and also demonstrate huge cost-savings for employers.  Join us as we take on “Big Pharma” this week on Self-Funded. Chapters: (00:00:00) Introducing Public Good Pharma (00:09:29) Our Profit-Driven Pharmaceutical Industry (00:12:16) Drug Development Challenges in Patent System (00:13:19) Patent Monopolies and “Evergreening” Pharmaceuticals (00:17:44) “Interventional Pharmacoeconomics” (00:19:32) Clinical Trials for Affordable Treatments (00:29:18) Employer Involvement in Lower-Cost Drug Trials (00:33:37) Cost-Effective Pharmaceutical Incentive Strategy (00:36:55) Revamping Healthcare Incentives (00:45:28) Affordable Pharmaceutical Alternatives Key Links for Social: @SelfFunded on YouTube for video versions of the podcast and much more - https://www.youtube.com/@SelfFunded Listen on Spotify - https://open.spotify.com/show/1TjmrMrkIj0qSmlwAIevKA?si=068a389925474f02 Listen on Apple Podcasts - https://podcasts.apple.com/us/podcast/self-funded-with-spencer/id1566182286 Follow Spencer on LinkedIn - https://www.linkedin.com/in/spencer-smith-self-funded/ Follow Spencer on Instagram - https://www.instagram.com/selffundedwithspencer/ Key Words:  #PharmaIndustry #DrugPricing #PatentSystem #Evergreening #ValueBasedPricing #InterventionalPharmacoeconomics #FormularyDesign #InnovativeIncentives #FixTheSystem #CostReduction #PersonalizedMedicine #AIinHealthcare #selffunded #podcast Pharma Industry, Drug Pricing, Patent System, Evergreening, Value Based Pricing, Interventional Pharmacoeconomics, Formulary Design, Innovative Incentives, Fix The System, Cost Reduction, Personalized Medicine, AI in Healthcare, self funded, podcast