This podcast explores the complications of diabetes caused by high blood glucose levels and focuses on the damaging effects on tissues such as the eyes, arteries, nervous system, and kidneys. It discusses the concept of glycation, the formation of advanced glycation end products (AGES), and their contribution to free radical damage, inflammation, and oxidative stress. The podcast also highlights the effectiveness of five vitamins (Benfotiamine, vitamin C, vitamin D, vitamin E, and vitamin B6) in inhibiting glycation and reducing diabetic complications, along with other nutrients and lifestyle factors.
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Quick takeaways
High blood glucose in diabetes can lead to complications in four main tissues: the eyes, the arteries, the nervous system (including the brain), and the kidneys.
Glycation and AGES formation can be mitigated through natural antioxidants and vitamins such as Benfotamine, vitamin C, vitamin D, vitamin E (tocotrienols), and vitamin B6.
Deep dives
Complications of Diabetes and Their Effects on the Body
High blood glucose in diabetes can lead to complications in four main tissues: the eyes, the arteries, the nervous system (including the brain), and the kidneys. These complications can result in vision problems, including blindness, as well as cardiovascular issues, nerve damage, digestive problems, and kidney failure. High blood glucose combines with proteins, causing glycation and the development of advanced glycation end products (AGES), leading to oxidative stress and tissue damage. These four tissues are particularly susceptible to AGES accumulation. Glycation and AGES formation can be mitigated through natural antioxidants and vitamins such as Benfotamine, vitamin C, vitamin D, vitamin E (tocotrienols), and vitamin B6.
Strategies to Reduce Glycation and Improve Diabetes Complications
In addition to vitamins, other compounds like alpha-lipoic acid, EGCG, aged garlic, bitter melon, quercetin, and curcumin can help reduce glycation. Consuming nutrient-dense foods like microgreens and following fasting protocols, including intermittent fasting and periodic prolonged fasting, can activate autophagy, which helps remove damaged proteins caused by glycation. Regular exercise is also beneficial in reducing glycation. To address the root cause of diabetes and improve glycation, adopting a healthy version of the ketogenic diet along with intermittent fasting is recommended.
Today I’m going to share five vitamins that can help with the complications of diabetes.
High blood glucose affects four main tissues, including:
1. The eyes
2. The arteries
3. The nervous system (including the brain)
4. The kidneys
However, the damage to these tissues can lead to a myriad of health problems.
Glycation is a combination of sugar and protein in the body, and it can lead to this dysfunction of tissues. An A1C score is basically a number that represents glycated hemoglobin (a protein in red blood cells) to help tell how bad someone’s diabetes is.
Glycation can also occur when someone consumes a combination of sugar or carbs and protein or fat.
When glycation occurs, it can build up into advanced glycation end products (AGEs). With AGEs comes a lot of free radical damage, inflammation, and oxidative stress.
The good news is that there are natural things that can inhibit glycation.
Vitamins that inhibit glycation:
1. Benfotiamine
2. Vitamin C
3. Vitamin D
4. Vitamin E (tocotrienols complex without tocopherols)