This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel.

Over the years, it has become a widely held belief that cancer is predominately a genetic disease or simply the consequence of bad luck. An empowering evolution in cancer research, however, suggests we have far more control over our risk than previously thought.

I’m excited to talk to Dr. Thomas Seyfried about the underlying causes of cancer and why addressing metabolic dysfunction is a very important and often overlooked area of its prevention and treatment.

Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. He received his Ph.D. from the University of Illinois Urbana-Champaign in 1976 and did his postdoctoral fellowship at the Yale University School of Medicine. Dr. Seyfried has over 150 peer-reviewed publications, and his research focuses primarily on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases and calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and presently serves on the Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro editorial boards.

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Here are more details from our interview (audio version / Apple Subscriber version):

How Dr. Seyfried’s work on treating epilepsy with a ketogenic diet informed his understanding of cancer (6:57 / 3:14)
Mitochondrial damage and cancer (16:58 / 14:44)
Glucose fermentation and oxidative stress and their links to cancer (25:52 / 24:47)
Our current misunderstanding of the cause of cancer (32:19 / 29:54)
Current cancer treatments vs metabolic oncology (38:31 / 36:50)
Populations without cancer incidence (56:10 / 51:55)
Metabolic cancer treatment for dogs (1:09:27 / 1:05:11)
Using a ketogenic diet with current cancer treatments (1:12:56 / 1:08:50)

Learn more at tomseyfried.com and at the Foundation for Metabolic Cancer Therapies.

Q&A: Macros or Calories? Muscles and Fasting for skinny guys? Fat burning foods? My go-to work lunch?