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Discovery

The Life Scientific - Peter Goadsby

Dec 9, 2024
Peter Goadsby, a leading neurologist and professor at King's College London, sheds light on the complexities of migraines, which affect over a billion people, predominantly women. He discusses the historical biases surrounding migraine perceptions and the urgent need for biological understanding. Goadsby shares insights on the innovative treatments emerging from his research, including monoclonal medications and the role of neuropeptides. His journey in medicine, from politics to pioneering migraine research, culminates in receiving the prestigious Brain Prize.
26:27

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Quick takeaways

  • Peter Goadsby's pioneering research has fundamentally changed the understanding of migraine mechanisms, leading to more effective treatment options for patients.
  • New treatments targeting calcitonin gene-related peptide (CGRP) represent significant advancements in alleviating both migraine attacks and preventing future occurrences.

Deep dives

Understanding Migraine as a Neurological Disorder

Migraine is a complex neurological condition that affects approximately one billion people globally. It involves abnormal brain function, leading to heightened sensitivity to light, sound, and even smell. The phenomenon known as 'migraine aura' affects around 20 to 30% of sufferers, presenting visual disturbances that signal an impending migraine. The condition is believed to have a genetic component, with hereditary factors influencing who may be prone to experiencing migraines, particularly evident among adult females.

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