
 The Peter Attia Drive
 The Peter Attia Drive #367 - Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data
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 Oct 6, 2025  This discussion tackles recent claims linking acetaminophen use during pregnancy to autism, clarifying the complexities involved. Peter emphasizes the significance of using structured frameworks to evaluate scientific evidence. He addresses the multifactorial nature of autism, noting genetics as a primary driver and examining other potential environmental contributors. Insights on how to interpret recent studies and the limitations they present are shared, alongside advice for pregnant women on medication use and critical thinking in health claims. 
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Use Frameworks To Interpret Epidemiology
- Humans are not naturally wired for scientific thinking so disciplined frameworks are required.
- Peter Attia recommends using tools like the Bradford Hill criteria to assess epidemiologic causality.
Complex Conditions Have Multiple Causes
- Complex conditions rarely have single causes and require multiple contributing factors.
- Peter Attia warns against assuming one exposure explains the rise in autism.
Follow A Three-Step Evaluation Process
- First confirm a statistical association exists before judging causality.
- Then assess likelihood of causality and effect size to decide actionable steps.
