The Wellness Messiah​ Podcast

NMN 2025: Everything You Thought You Knew About It Is Wrong  | New Study Analysis

5 snips
Dec 23, 2024
A groundbreaking study reveals surprising truths about NMN and its impact on lifespan, particularly highlighting gender differences in effectiveness. Female mice show significant benefits, while males experience no notable gains. The discussion stresses the importance of tailored approaches to supplementation, emphasizing NAD recycling techniques like fasting and exercise. There’s also a call for greater inclusivity in scientific research, advocating for balanced representation to deepen our understanding of sex-based responses. Is it time to rethink your approach to longevity?
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INSIGHT

NMN and Lifespan in Male Mice

  • NMN did not increase the lifespan of male mice in a new study, despite researchers' efforts to show benefits.
  • The study, subsidized by Metro Biotech, administered high doses of NMN but still yielded no lifespan increase for males.
INSIGHT

NMN and Lifespan in Female Mice

  • Female mice experienced an 8.5% increase in median lifespan and a 7.9% increase in maximum lifespan with NMN.
  • This contrasts sharply with the results in male mice, suggesting sex-specific effects of NMN.
ADVICE

Dividing NMN Doses

  • Consider dividing NMN doses throughout the day instead of taking it all at once.
  • This mimics natural NMN delivery, such as in breast milk, and may align better with the body's NAD consumption cycle.
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