JAMAevidence JAMA Guide to Statistics and Methods

Adjustment for Baseline Characteristics in Randomized Clinical Trials

Dec 7, 2023
Lars W. Andersen, a medical doctor and researcher, discusses adjusting for baseline characteristics in randomized clinical trials. They explore the concept of confounders, the importance of adjusting for baseline characteristics, and different approaches to adjustment. They also discuss the impact of adjusting baseline characteristics on treatment effect estimates and highlight the significance of this adjustment for accurate interpretation of trial results.
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