Trial of the Week: SPLIT
Special Guest: Anthony Hawkins, PharmD, FCCM, BCCCP
Anthony Hawkins joins me to highlight the “Effect of a Buffered Crystalloid Solution vs. Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial” published in JAMA.
We compare the composition of different crystalloids, review pertinent trials published prior to this study, discuss the findings from the SPLIT RCT, what is the best primary outcome in these studies, research on the horizon, questions to be answered, and much more.
Reference list: https://pharmacytodose.files.wordpress.com/2023/10/split-tow-references.pdf
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