All Things Testosterone

Semaglutide, Tirzepatide, and Mental Health Benefits of TRT

Jan 16, 2023

This podcast explores the medications Semaglutide and Tirzepatide for diabetes treatment and weight loss. It discusses their mechanism of action, effectiveness in promoting weight loss, and side effects. The podcast also touches on personal experiences with weight loss, the importance of routines, the impact of caffeine, and dairy intolerance. Additionally, it shares a personal testimonial about the mental health benefits of Testosterone Replacement Therapy (TRT) in overcoming social anxiety and becoming more expressive.

24:07

Creator website

AI Summary

AI Chapters

Episode notes

Podcast summary created with Snipd AI

Quick takeaways

Semaglutide and Tirzepatide are FDA-approved weight loss medications that mimic GLP-1 class hormones, reducing hunger and promoting weight loss.

Testosterone Replacement Therapy (TRT) has shown positive effects on reducing anxiety and enhancing confidence levels, allowing individuals to feel more at ease in social interactions.

Deep dives

The Benefits of Some Magletide and Terzepitide for Weight Loss

Some Magletide and Terzepitide are medications that have been FDA-approved for weight loss. Some Magletide mimics GLP1 class hormones, which regulate digestion and metabolism. It helps make you feel full and reduces hunger. Terzepitide, also known as Manjaro, has a dual effect on GLP1 and GIP, further enhancing weight loss. Studies have shown significant weight loss of up to 22.5% over a year with these medications. Side effects may include diarrhea, nausea, constipation, and vomiting. However, some individuals have reported discomfort while eating and feeling bloated. The medications seem to be effective in reducing cravings and habitual eating.

Introduction

5min

Semaglutide, Ozempic: Diabetes Treatment and Weight Loss

6min

Weight Loss, Routines, and Cravings

5min

Dairy intolerance and preferences

7min

Personal Experience with Mental Health Benefits of TRT

2min

The All Things Testosterone podcast is a product of the TRT Community. We are the world's largest online support system for men and women undergoing Testosterone Replacement Therapy, or "Patients Helping Patients." Join our FREE Facebook group below!

On today's episode we discuss the following:

Semaglutide (Wegovy) and Tirzepatide (Mounjaro)
TRT Mental Health Benefits
Anxiety

TRT Community Post - I posted this short blog, about weight loss drugs in the TRT Community Facebook group. The first sentence was something like, "Losing weight can be an incredibly difficult endeavor…" A fellow responded and informed me that losing weight is not difficult and a conversation ensued.

Just because something has a step process you can follow, doesn't make it easy. I could rebuild a transmission with the proper instructions, but there's a reason specialty shops exist. Have you ever had a pack of clutch plates laying on a work bench???

Topic One: Semaglutide & Tirzepitide

Semaglutide -

it's sold as Ozempic and Rybelsus for DM treatment and Wegovy for weight loss.
Brain uses hormones to regulate functions, including digestion and metabolism
Semaglutide mimics the action of GLP-1 class hormones

GLP-1, or glucagon like peptide-1 help regulate digestion and metabolism

The more GLP-1, the more full you are

Side effects - Diarrhea, Nausea, Constipation, vomiting

Tirzepatide

(Mounjaro) currently approved for DM treatment

Same GLP-1 effects as Semaglutide

Also effect on GIP (glucose=dependent insulinotropic polypeptide)

GIP enhances the action of GLP-1, which tells the brain to stop eating.
The way I think about it is like this: Semaglutide, Ozempic, Rybelsus, Wegovy - it's like having a fellow in your brain telling you to stop eating. Tirzepatide or Mounjaro is like have 2 fellows in your brain TELLING you to stop eating.

The most effective weight loss medication ever made available with an average weigh tloss of 22.5% over the course of a year.

Personal experience - started taking Semaglutide about 7 months ago. Lost about 10% BW in a few months and plateaued. Started Tirzepatide this month. Not much side effects. Feeling bloated/full most of the time

Tirzepatide highly effective for weight loss - PubMed (nih.gov)

Facebook Questions:

Did TRT improve your anxiety and confidence? Maybe is the fact that I’m autistic, but all my life Ive been prone to being anxious when interacting with others regardless of how many times I do it. I’m 38 and even if I’m “relaxed” there is still a “slight” anxiety underneath that’s probably unseen by others yet I feel it. Maybe I’m just a nervous person but I have noticed my anxiety has gotten worse compared to 10 years ago. I feel more confident than when I was younger from life experience and maturity but still anxious. I’m also more prone to being fearful than some but I fight it and contain it. I wish I was like those guys seem to have no fear and have nerves of steel. That’s life but who knows maybe i have a bigger weiner or higher IQ than them.

So many folks focus on the physical improvement aspects of TRT. The mental health benefits are what I'm most passionate about. Before TRT - I was anxious daily, no confidence, counting hours before I had to do things like go to work, afraid to speak up, engage people in social situations, seeking validation from other people and manipulating them into providing you with value. I was super impatient. Here's a quick video of my after experience

Before and After Testosterone Replacement Therapy

Thanks for listening! Please rate, review, subscribe and join our FREE Facebook community below!

TRT Community Private Facebook Group

Take a Free Glucose Quiz

Find a TRT Doctor