a16z Podcast

What Super Agers Reveal About Preventing Disease

394 snips
May 14, 2025
Dr. Eric Topol, founder of the Scripps Research Translational Institute and a leading figure in preventive healthcare, reveals groundbreaking insights about longevity. He discusses the concept of 'Super Agers'—those who thrive into old age—and the importance of understanding aging biology to prevent major diseases. Topol highlights the role of AI in health predictions, personalized medicine, and lifestyle changes necessary for enhancing healthspan. He advocates for a shift from reactive care to proactive, precision prevention to combat age-related conditions.
Ask episode
AI Snips
Chapters
Books
Transcript
Episode notes
INSIGHT

Prevention Over Aging Reversal

  • Preventing age-related diseases is more achievable than reversing aging itself.
  • Focusing on preventing cancer, cardiovascular, and neurodegenerative diseases can extend healthspan significantly.
INSIGHT

Long Incubation Of Age Diseases

  • Many major age-related diseases incubate for up to 20 years before symptoms appear.
  • A defective immune system and inflammation are common underlying factors in these diseases.
ADVICE

Leverage AI And Biology Data

  • Use AI to integrate complex biological data for personalized health insights.
  • Employ omics, cell therapies, and immune system control to prevent and treat diseases.
Get the Snipd Podcast app to discover more snips from this episode
Get the app