Science Friday The Leap: Garbage In, Garbage Out
Jun 16, 2025
Biochemist Virginia Man-Yee Lee, renowned for her groundbreaking work on neurodegenerative diseases, shares her inspiring journey from a musical upbringing in Hong Kong to a pivotal career in science. She emphasizes the importance of happiness in achieving success. Joined by neurologists Ken Kosick and Alice S. Chen-Plotkin, they delve into the challenges of Alzheimer's research and the vital discoveries about proteins like TDP-43. Their collaboration showcases the power of teamwork and the determination required to advance medical understanding.
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Virginia's Remarkable Early Life
- Virginia Man-Yee Lee was born on the roadside during a wartime escape, almost aborted by her mother.
- She grew up mostly on her own, being raised by aunts and uncles after her parents moved away.
Breaking Barriers in Science
- Virginia broke barriers as an Asian woman in science, becoming one of the very few women honored in her medical school.
- She faced many obstacles but carved a successful path in neurodegenerative disease research.
Partnership in Life and Science
- Virginia met her scientific and life partner John Trojanowski in a bar; they quickly formed a personal and professional partnership.
- They chose to prioritize research over having children, dedicating themselves fully to science.