This Podcast for the Neurology Journal begins with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andrew Southerland and Dr. Jennifer Bickel interview Dr. Marcelo Bigal about his paper on the clinical course in migraine. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week. The podcast concludes with Dr. Richard Isaacson interviewing Dr. Stephen D. Silberstein about headache classification for the Lesson of the Week segment. The participants had nothing to disclose except for Dr. Silberstein.Dr. Silberstein is an investigator for the following companies: Abbott, Advanced Bionics, Advance Neur0-Modulation System, AGA, Allergan, AstraZeneca, Endo Pharmaceuticals, GSK, Lilly, Medtronic, Ortho-McNeil, Pfizer, Pozen, ProEthic, Valeant & Vernails, on theadvisory board for the following companies: Allergan, Endo Pharmaceuticals, GSK, Medtronic, Merck, NuPathe, Ortho-McNeil, Pfizer, Pozen & Valeant and speaker for the following companies: AstraZeneca, GSK, Merck, Ortho-McNeil & Pfizer.