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20VC: Bryan Johnson on Why Humans Are No Longer Qualified to Manage Our Own Affairs, How Algorithms Will Run our Bodies and How to Process New Ideas and Challenge Conventional Beliefs

Mar 22, 2024

Bryan Johnson discusses how humans are ill-equipped to manage their affairs, the concept of immortality, and the importance of challenging conventional beliefs. He shares insights on using algorithms for self-care, his approach to processing new ideas, and the role of religion in society. Johnson also explores the potentials of AI in human longevity and shares personal anecdotes on parenting, sleep optimization, and the quest for prolonged life.

52:06

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Episode guests

Bryan Johnson

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Quick takeaways

Humans are unfit to manage their own affairs, new ideas must be tested with 3 questions, AI will play a crucial role in human longevity.

Deep dives

Controlling Life and Death

Brian Johnson, a founder who invested $100 million in genomics, delves into life engineering and reversing aging. He embraces an algorithm that surpasses his judgment, aiming to be respected by the 25th century. Johnson's approach challenges prevailing beliefs, advocating vigilance in processing new ideas, and exploring the unrevealed self post new idea encounters.

Preserve Conscious Existence

01:05

Clarity of thought through good sleep

01:19

Reframe Your Identity to Improve Sleep

01:06

Continuous Pressure Testing for Validity

00:47

Introduction

3min

Exploring the Process of Processing New Ideas and Challenging Conventional Beliefs

2min

Navigating Change and Internal Conflict

7min

Embracing Uncertainty and AI Management

22min

Loneliness, Religion, and Social Cohesion

5min

Exploring the Quest for Prolonged Life and Societal Adjustments

4min

The Era of Algorithmic Influence

7min

Promotion of Notion, Digis, and Navan AI tools for workflow automation and financial management

3min

Bryan Johnson is the founder of Blueprint, the man is at war with death and is mastering longevity. Bryan is on a mission aimed at enhancing human intelligence and being respected by people in the 25th century. Before starting Blueprint, Bryan also founded Braintree (acquired by PayPal for $800M) and OS Fund – a $100M venture capital fund investing in genomics, synthetic biology, and complex systems.

In Today’s Episode with Bryan Johnson We Discuss:

The Philosophy of Don’t Die

What does Bryan think is the biggest existential threat to humankind?
Why does Bryan believe humans are unfit to manage their own affairs?
Why does Bryan care about being liked by the 25th century?
Does Bryan think society is ready to adapt to immortality?

How to Process New Ideas

What 3 questions does Bryan ask to test new ideas?
How does Bryan combat against his own biases?
How does Bryan adapt to change? What has been his most painful experience?
Why does Bryan think religion is humanity’s most durable technology?

The Most Measured Human in the World

What did Bryan learn about himself as the most measured human in the world?
How does Bryan use algorithms to take care of himself?
What has been Bryan’s most expensive test?
How did Bryan use data to rejuvenate his sexual function?
How will tech & AI play a role in human longevity?

Health & Parenting Advice

How does Bryan raise his children?
How does Bryan get perfect sleep every night? What are his tips?
What is Bryan’s advice to people who think it’s too late to start becoming healthy?
What health advice does Bryan think is BS?

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