178. Isabelle Kenyon, Founder & CEO of Calibrate

Today, I’m joined by Isabelle Kenyon, founder & CEO of Calibrate, a weight loss platform complementing lifestyle coaching with prescription medication.

Calibrate helps people achieve sustainable weight loss and metabolic health through personalized clinical and lifestyle interventions. Founded in 2020, the company’s evidence-based programming, expert coaching, and FDA-approved GLP-1 medication has positioned it as a leader in taking on the obesity epidemic.

In this episode, we discuss the company’s metabolic reset program, explore the rapid growth of prescription weight loss drugs, and cover the ongoing debate over how best to treat obesity.

In this episode, you’ll learn:

• Why Calibrate believes weight loss is about biology, not willpower • The company’s methodology for prescribing GLP-1 medication • Isabelle and Joe’s perspectives on healthy weight loss and prescription medication

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Chapters: (00:00) Introduction (01:15) About Calibrate (02:39) Enterprise vs. DTC business model (03:39) GLP-1 potential TAM (05:10) What differentiates Calibrate? (08:29) Finding the ideal long-term care model for patients (12:59) Is obesity about willpower or biology? (19:01) Metabolic health and food  (23:07) GLP-1’s that are covered by insurance (26:20) If the product works, the business works (29:35) Scaling Calibrate (30:54) Systemic obesogenic environment (35:13) Future roadmap (37:44) Conclusion