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This podcast explores maintaining strength over a lifetime and discusses topics such as anabolic resistance and age-related muscle decline, the impact of aging on muscle mass and strength, the positive effects of resistance training, and the challenges of meal planning for older individuals.
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Quick takeaways
- Anabolic resistance, caused by cellular-level processes and reduced satellite cell activity, leads to muscle loss in older individuals.
- Resistance training, with proper frequency, volume, and intensity, can counteract age-related muscle loss and anabolic resistance, making it an effective anti-aging strategy.
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Mechanisms of anabolic resistance in aging individuals
As individuals age, they tend to become more anabolically resistant, meaning that their muscle protein synthesis and breakdown in response to stimuli like exercise or dietary protein become blunted. This resistance is not due to absorption or blood flow issues but rather related to cellular-level processes and reduced satellite cell content and activity. Increased fat deposition and inflammation also contribute to the anabolic resistance. These mechanisms lead to a loss of muscle mass and strength in older individuals.
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highlights
Listen to the best highlights from the podcasts you love and dive into the full episode