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H. Pylori Is Necessary But Not Sufficient
- H. pylori infects the stomach lining and causes chronic inflammation that can lead to stomach cancer.
- Yet about half the world is infected while only a minority develop cancer, implying other cofactors matter.
The African And Indian Enigmas
- High H. pylori prevalence doesn't always mean high stomach cancer rates, as seen in Africa and India.
- This suggests diet or other environmental cofactors interact with H. pylori to determine cancer risk.
Salted And Pickled Foods Amplify Risk
- Preserved, salted, and pickled foods associate with higher stomach cancer odds while fresh fruits and vegetables are protective.
- Salt may damage the mucus layer and enhance H. pylori colonization and carcinogen penetration.