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Breakpoints

#96 – The Tortured Stewards & Surgeons Department

Apr 19, 2024
Join Trisha Peel, Michael Calderwood, and Patch Dellinger in a lively discussion on perioperative antibiotic management and surgical site infection prevention. Delve into controversies like post-op antimicrobial prophylaxis duration, vancomycin use, and pre-op cefazolin for penicillin-allergic patients. Learn about the importance of judicious antibiotic use in optimizing patient care and collaboration between surgery and antimicrobial stewardship for better outcomes.
01:06:21

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Quick takeaways

  • Optimal management of perioperative antibiotics is crucial to prevent surgical site infections.
  • Screening for MRSA colonization and decolonization strategies are essential in infection prevention protocols.

Deep dives

The Impact of Duration and Type of Post-Op Antimicrobials

The podcast explored the impact of duration and type of post-operative antimicrobials on patients undergoing surgery, emphasizing that every additional day of antimicrobial use matters. Research highlighted in the episode showed that increasing the duration of surgical prophylaxis did not reduce surgical site infections and was associated with increased risks of acute kidney injury and Clostridium difficile infections. New guidelines suggested discontinuing antimicrobial prophylaxis at the time of surgical closure to mitigate these risks.

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