The Dr. Hyman Show

The One Factor That Determines 90% Of Your Risk For Disease with Dr. Todd LePine

Aug 17, 2020
Dr. Todd LePine, a board-certified internist specializing in Integrative Functional Medicine, unveils the concept of the exposome—total lifetime exposures affecting health. They discuss the significant role of environmental toxins, like heavy metals, in chronic diseases, including neurodegenerative conditions. The conversation highlights a functional medicine approach to detoxification and the balance of gut health and nutrition. LePine also explores how lifestyle choices, not just genetics, can empower better health outcomes.
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INSIGHT

Exposome Definition

  • The exposome, encompassing all lifetime exposures, significantly influences health and gene expression, starting in utero.
  • Exposures range from diet and environmental toxins to thoughts and emotions.
ANECDOTE

George Burns Gene

  • Dr. LePine highlights the "George Burns gene," referring to people who age well despite exposures like alcohol and cigars.
  • He cites George Burns and his own father as examples of individuals with good detoxification abilities.
INSIGHT

Toxicology

  • Traditional toxicology focuses on high doses, deeming substances safe if they don't cause cancer at those levels.
  • However, low doses of toxins like BPA can disrupt the endocrine system.
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