AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
251 | Rosemary Braun on Uncovering Patterns in Biological Complexity
Sep 25, 2023
01:11:18
Snipd AI
Biophysicist Rosemary Braun discusses uncovering patterns in biological complexity using large datasets. Topics include collective behavior within organisms, timekeeping and its implications, advancements in genomic sequencing and proteomics, gene expression and protein interaction variation, challenges of understanding gene functionality, the role of computers and machine learning in analysis, the use of large datasets in analyzing complex biological systems, circadian rhythms and their impact, the transcription-translation feedback loop in mammals and fruit flies, and analyzing complex systems and biological complexity.
Read more
AI Summary
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- Circadian rhythms are maintained by molecular oscillators within each cell and their communication mechanisms are not fully understood.
- Advancements in micro and molecular biology profiling technologies provide vast amounts of omics data to explore connections between genes, proteins, and pathways.
Deep dives
The Ubiquity of Circadian Rhythms
Circadian rhythms, which govern the internal clocks in our bodies, are present in nearly every cell. These rhythms are maintained by a molecular oscillator within each cell, which consists of genes that are transcribed and translated into proteins. These proteins then regulate the transcription of other genes in a negative feedback loop, sustaining oscillations. This ubiquitous presence of circadian rhythms raises questions about why every cell has its own clock and how they communicate with each other. While the exact mechanisms of communication are not fully understood, signaling molecules like melatonin and the nervous system play a role. Additionally, studies have shown that external cues like exercise can influence the phase of circadian rhythms in certain tissues. The complexity of these chemical networks and the multitude of genes controlled by the clock highlight the integrated nature of circadian rhythms within the larger biological system.
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode