In this episode called "Norepinephrine: How High Can You Go," Dr. Salim Rezaie explores the complexities surrounding the maximum dosage of norepinephrine in critical care scenarios. Through an analysis of retrospective studies and a remarkable case report, Dr. Rezaie highlights the lack of definitive evidence and consensus on upper limits, shedding light on survival rates and associated outcomes at varying dosages. Emphasizing the importance of cautious escalation and thorough patient assessment, he provokes thoughtful discussion within the ResusX community, aiming to deepen understanding and enhance patient care strategies in emergency medicine and critical care settings.