Instant Genius cover image

Instant Genius

How science is tackling one of the most common causes of sight loss

Feb 7, 2025
Professor Richard Gale, an expert in age-related macular degeneration from Hull York Medical School, discusses the impact of this common sight loss condition, affecting many, including Dame Judi Dench. He highlights early warning signs and the necessity of regular eye exams. Gale shares insights on the differences between wet and dry forms of AMD, treatment advancements like genetic therapy, and innovative drug delivery methods. His optimism about emerging therapies offers hope for enhancing the quality of life for those at risk.
28:16

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Quick takeaways

  • Early detection through regular eye examinations is crucial for managing age-related macular degeneration and preventing its progression.
  • Advancements in treatment options, including injection therapies and potential gene therapies, offer optimism for improving outcomes for AMD patients.

Deep dives

Understanding Age-Related Macular Degeneration

Age-related macular degeneration (AMD) primarily affects the central part of the retina known as the macula, which is essential for sharp vision. Common signs of AMD include difficulty seeing fine details, needing more light to read, or a gradual decline in visual quality, especially in individuals over 50. Diagnosis usually occurs during routine eye examinations, where optometrists observe changes in the retina that signify the early stages of the condition. Continuous monitoring and early detection are crucial in managing AMD effectively and preventing progression.

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