Certain medications, including lithium, quetiapine, and clozapine, have been found to increase life expectancy and improve physical health for individuals with bipolar disorder.
Clozapine, despite its potential dangerous side effects, has been shown to extend the lifespan of individuals with schizophrenia by an average of 10 years compared to other antipsychotic medications, likely due to its ability to bring about a more complete recovery from the illness and improve overall physical health.
Deep dives
Medications that help patients live longer with bipolar disorder
The podcast discusses how certain medications, including lithium, quatiopine, and clozapine, can help patients with bipolar disorder live longer. Despite the medical risks associated with these medications, studies have shown that they are associated with an increase in life expectancy for individuals with bipolar disorder. The medications primarily target depressive symptoms, which make up a significant portion of the lifespan in bipolar disorder. By effectively treating the mental illness, these medications contribute to better physical health and longer lives for patients.
The surprising benefits of clozapine in schizophrenia
The podcast highlights the remarkable benefits of clozapine, an antipsychotic, in extending the lifespan of individuals with schizophrenia. Despite its potential dangerous side effects, including agranulocytosis and paralytic ileus, studies have shown that patients who take clozapine live an average of 10 years longer compared to those on other antipsychotic medications. Clozapine is believed to bring about a more complete recovery from schizophrenia and improve overall physical health, leading to increased longevity.
Balancing risks and benefits of medications in psychiatry
The podcast emphasizes the importance of balancing the risks and benefits of medications in the field of psychiatry. While medications such as lithium, quatiopine, and clozapine carry certain risks, including metabolic problems and other side effects, they have been found to significantly benefit patients by extending their lives. The podcast highlights that the quality of life is also crucial, and despite common misconceptions about the tolerability of these medications, many patients have experienced significant improvements in their mental health and overall well-being with the use of lithium and clozapine. The adherence rates for lithium and clozapine were found to be higher compared to other medications, indicating patient preference and the positive impact these medications have had on their lives.
Chris Aiken, MD, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.
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