ADHD Experts Podcast 575- An Adult’s Guide to ADHD Treatment Considerations
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Sep 16, 2025 
John Kruse, MD, PhD, is a seasoned ADHD expert who has spent over 30 years treating adults in San Francisco. He shares insights on the nuances of ADHD medications, comparing stimulants and non-stimulants while discussing their side effects. Kruse emphasizes the importance of personalized treatment, especially for older adults. He also highlights the intersection of ADHD and OCD, explores alternative treatments like supplements, and clarifies common misconceptions about medication risks. His depth of knowledge sheds light on navigating the complexities of adult ADHD.
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Lifestyle Is Core To ADHD Treatment
- ADHD treatment must combine medication with lifestyle changes like sleep, exercise, and diet.
- John Kruse emphasizes sleep as the single most important lifestyle factor for executive function.
Stimulant Means Different Things
- 'Stimulant' is a broad term but ADHD medicine discussion uses a narrower definition focused on drugs that boost neurotransmitter release.
- Kruse distinguishes strong stimulants (amphetamine-like) from broader sympathomimetics like caffeine.
Amphetamines Tend To Be Most Effective
- Strong stimulants outperform other ADHD treatments and work better overall than non-drug options.
- Studies suggest amphetamine products are more effective than methylphenidate across age groups.