Is TRT Heart Safe? | The Gillett Health Podcast #40

On today's podcast Dr. Gillett and James O'Hara NP, Discuss the pros and cons of TRT.

00:00 Intro

01:54 First study

04:45 Testosterone levels achieved

06:35 Risk factors

08:39 Potential harm

12:35 Relative risk and absolute risk

14:13 Afib non-fatal arrhythmia

18:13 Acute kidney injury

18:52 Diabetes

20:16 Blood pressure

21:00 Red blood cells

27:20 Hematocrit changes with different forms of TRT

30:43 DHT

33:58 Nasal TRT

36:50 Thromboxane A2

40:52 Testosterone gel increases Plac?

43:21 SubQ

45:41 Different ways to administer

54:41 Studies we would like to see/closing thoughts

59:26 Outro

Studies/References

► https://www.nejm.org/doi/full/10.1056/NEJMoa2215025

► https://www.auajournals.org/doi/10.1097/JU.0000000000002437

► https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621711/

► https://www.ahajournals.org/doi/full/10.1161/circulationaha.114.012066

► https://www.goldjournal.net/article/S0090-4295(20)31480-1/fulltext

► https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864697/

► https://pubmed.ncbi.nlm.nih.gov/34445892/

► https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690890/

► https://academic.oup.com/qjmed/article/98/5/349/1561336

► https://jamanetwork.com/journals/jama/fullarticle/2425744

► https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14051

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