This Week in Neuroscience

TWiN 51: Sensory processing dysfunction in autism spectrum disorders

15 snips
May 28, 2024
The podcast discusses altered somatosensory reactivity in autism spectrum disorders, predicting ASD behaviors in mouse models. They explore touch processing in mice, inhibition in sensory pathways, genetic mutations related to ASD, and interventions for touch hypersensitivity. The hosts share personal experiences with sensory sensitivity and delve into the complexities of sensory processing dysfunction, environmental influences, and gene associations in ASD.
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INSIGHT

Sensory Processing in ASD

  • Sensory processing differences are a major feature of neurodevelopmental disorders, especially autism.
  • Studying sensory processing in mice helps to understand the diverse symptoms and severities of ASD.
INSIGHT

Prevalence of Sensory Dysfunction

  • Sensory processing dysfunction affects 94% of individuals with ASD, impacting various sensory modalities.
  • This dysfunction may underlie social and cognitive challenges by hindering the brain's ability to process sensory input.
ANECDOTE

Hypersociality in ASD

  • Some individuals with ASD exhibit hypersocial behavior, lacking boundaries and stranger danger awareness.
  • This contrasts with the more common social withdrawal seen in ASD, highlighting the spectrum's diversity.
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