Understanding Inhibition in Sensory Processing and Motor Output Pathways

This chapter delves into the complexities of inhibition in neuroscience, focusing on primary sensory afferents, dorsal spinal neurons, and motor efferents. It discusses the impact of inhibition on neural connections and different neurotransmitters like GABA and glycine, as well as the spatial and temporal restrictions of inhibitions in the brain. The chapter also explores the role of neuro ligand 2 (NL2) in sensory processing dysfunction in autism spectrum disorders, highlighting genetic tools like the Cre-Lox system to study inhibitory receptor components like GABRB3 and NL2.