
Extend Podcast with Darshan Shah, MD 130. Smarter Drinking: Cut Alcohol Without Sacrifice
Jan 15, 2026
Explore the science behind smarter drinking and its impact on health. Learn how alcohol disrupts sleep and metabolism, and why timing matters. Simple strategies like stopping drinking hours before bed and pacing yourself can yield big benefits. Discover the power of non-alcoholic options, and how food can help manage alcohol intake. Dr. Shah also discusses the role of medical tools like naltrexone and GLP-1s in reducing cravings. Small, consistent changes can lead to real improvements in overall wellbeing.
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Hidden Early Harms Of Regular Drinking
- Alcohol causes early, subtle harms that accumulate before liver disease appears.
- It disrupts sleep, recovery, cognition, mitochondria, microglia, and the microbiome over time.
Stop Drinking Four Hours Before Bed
- Stop drinking at least four hours before bedtime to protect sleep quality.
- This timing reduces REM suppression, sleep fragmentation, and next-day hangover severity.
Pace Drinks—Give Your Liver Time
- Slow your drinking pace and space drinks 90–120 minutes apart.
- One standard drink takes ~2 hours to metabolize, so faster drinking raises blood alcohol levels and harms.
