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Docs Who Lift

Microdosing GLP-1 and Cagrisema headlines

Dec 23, 2024
Delve into the intriguing concepts of microdosing GLP-1 receptor agonists and the latest results from a new weight loss drug. Discover the balance between ethical medication access and corporate practices in healthcare. Hear about the eccentric quest for longevity and the disparities in medication availability. Explore the implications of microdosing terzepatide on inflammation versus weight loss. Unpack the ethical concerns surrounding cosmetic weight loss medications and the importance of responsible pharmaceutical practices.
40:20

Podcast summary created with Snipd AI

Quick takeaways

  • Microdosing GLP-1 receptor agonists could minimize side effects while still providing therapeutic benefits, showcasing the need for personalized treatment approaches.
  • The promising results from the CagriSema trials highlight the movement towards combination therapies in obesity treatment, potentially leading to more effective weight loss outcomes.

Deep dives

Recent Developments in Obesity Medications

Novo Nordisk faced a significant drop in stock prices due to unmet expectations regarding its weight loss medication, which fell short of a 25% total body weight loss target in trials. Semaglutide and terzepatide are currently seeing weight loss results around 15% and 21%, respectively, which are still considerable compared to earlier obesity medications. The podcast discusses how past generations of obesity treatments, like loraglutide, would have been celebrated for achieving similar results. These developments provide insight into the competitive landscape of obesity drugs and highlight the advancements made in recent years.

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