Science Friday Could The NIH Plan For A ‘Universal Vaccine’ Really Work?
May 28, 2025
Join infectious disease expert Michael Osterholm and vaccine researcher Ted Ross as they delve into the NIH's ambitious plan for a universal vaccine. They discuss the potential of a single shot for flu and COVID-19 that could last for years. The conversation covers the challenges of vaccine development, addressing public hesitancy, and the innovative COBRA program that uses AI in vaccine design. With clinical trials on the horizon, they explore the complexities of ensuring trust and efficacy in public health strategies.
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Science vs PR in NIH Plan
- The NIH's Generation Gold Standard plan is seen by experts as more public relations than a science breakthrough.
- The U.S. already has gold standard science with many NIH-supported Nobel laureates working on vaccines.
Virus Biology Shapes Vaccines
- Virus biology like genetic diversity dictates vaccine complexity and duration of immunity.
- Vaccines for highly variable viruses like flu and COVID need updates, unlike some lifelong vaccines.
Combat Vaccine Hesitancy Proactively
- Communicate clearly about vaccine science to address hesitancy.
- Support healthcare workers who spend more time combating vaccine misinformation with patients.