AFP: American Family Physician Podcast Episode 240 -- October 2025 -- Part 2 AFP: American Family Physician
Oct 31, 2025
Dakota Wise, a guest presenter and expert on mental health guidelines, dives into the latest CanMAT updates on managing major depressive disorder. The discussion highlights tailored treatment approaches, the importance of psychotherapy, and effective measurement with PHQ-9. The podcast also tackles the potential overuse of colorectal cancer screenings, innovative anticoagulation strategies for hospitalized COVID-19 patients, and crucial insights on diagnosing slipped capital femoral epiphysis. This insightful conversation blends clinical guidelines with practical implications for healthcare.
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Colonoscopy Benefits And Overuse
- Colonoscopy has high sensitivity and can remove adenomas, but harms and overuse are common.
- Over 2 million unnecessary colonoscopies yearly cause about 9,000 serious harms in the U.S.
Use Evidence-Based Screening Intervals
- Work with patients and GI colleagues to ensure colonoscopies occur at evidence-based intervals.
- Use shared decision making and offer stool tests when appropriate because the best screening test is the one that gets done.
Start Mild Depression With Exercise Or Therapy
- For mild depression, try 30–40 minutes of low–moderate exercise 3–4 times weekly for at least nine weeks before medications.
- Use psychotherapy (12–16 sessions) and tailor treatment intensity to severity.