Commune with Jeff Krasno

447. Unlocking the Psychedelic Puzzle: Serotonin, Ketamine, and the Future of Mental Health with Dr. Dave Rabin, PhD

Jun 15, 2023

Dr. Dave Rabin, a psychedelic healthcare expert, discusses the potential of psychedelic-assisted therapy for mental illnesses. Topics covered include the misconceptions surrounding serotonin and its relationship to depression, the benefits of ketamine in increasing neurogenesis and neuroplasticity, and different administration methods for ketamine. The podcast also explores the impact of chronic stress on gene expression and the need for a shift in the perception and treatment of mental illness.

02:20:09

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Episode guests

Dave Rabin

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Episode notes

Podcast summary created with Snipd AI

Quick takeaways

Creating a safe environment is crucial for activating the parasympathetic nervous system and promoting healing and growth.

Neuroplasticity plays a significant role in addressing mental illness by rewiring the brain through the creation of new neurons and synapses.

Studies show that burst activation of serotonin receptors in psychedelic therapy may have a more profound impact on mental health than serotonin imbalance.

Prioritizing safety and utilizing neurocatalytic agents can unlock the brain's potential for healing and growth in addressing mental illness.

Creating a balance between alertness and calmness is crucial for optimal neurochemical balance and promoting a safe environment for learning.

Deep dives

The Importance of Safety in Neurocatalytic Therapy

Safety is crucial in neurocatalytic therapy as it allows the body to activate its parasympathetic nervous system, which is responsible for recovery, rest, and creativity. By creating a safe environment, the body can shift its focus from fight-or-flight responses to activities that promote healing and growth.

The Effects of Exposure Therapy on Neural Networks

01:20

Anxiety and Depression

01:20

Introduction

2min

The Potential Benefits of Ketamine Assisted Therapy for Mental Health Conditions

3min

Advancements in Mental Health Treatment

14min

Apollo Wearable for Stress Relief and Sleep Improvement / Mechanism of Transgenerational Epigenetic Inheritance

5min

The Impact of Chronic Stress on Gene Expression

14min

The Medicalization of Psychedelics and the Complexity of the Brain

3min

Serotonin and its Role in Mental Health

13min

Exploring the Effects of Psychedelic Therapy on Brain Function

3min

Unlearning and Relearning for Mental Well-being

26min

10.

Expanding vs Preserving and the Connection to Stoicism

3min

11.

Exploring the Challenges of Meditation and the Importance of Other Therapies

4min

12.

Ketamine: An Anesthetic and Antidepressant

25min

13.

Different Protocols for the Administration of Ketamine

12min

14.

Administration and Impact of Ketamine for Psychedelic Medicine

21min

15.

Promoting Dr. Dave's Neuroplasticity Course and Thrive Market, and Thanking the Team

4min

Dr. Dave Rabin is at the forefront of psychedelic healthcare. In this episode we unravel the misconceptions surrounding serotonin and its relationship to depression, highlighting studies that suggest psychedelic-assisted-therapy may provide long-term healing and possibly a cure for some mental illnesses. Learn why ketamine is found to increase neurogenesis, neuroplasticity, and the formation of new connections between neurons, which are believed to contribute to its therapeutic potential.

In this episode we cover:
0:05:01 – Mental Disorders
0:12:39 – Is Mental Illness Genetic?
0:14:36 – Epigenetics
0:15:57 – Trauma
0:19:46 – Transgenerational Epigenetics
0:28:45 – Exposure Therapy
0:32:19 – Is Mental Illness a Biochemical Imbalance?
0:33:45 – Serotonin
0:49:00 – How Effective Are SSRIs?
0:53:49 – Psychedelic Medicine
0:57:34 – Neuro-Catalytic Agents
1:10:38 – Neuroplasticity
1:16:29 – Newness as Threat
1:24:41 – Meditation
1:30:21 – Ketamine-Assisted Therapy
2:04:38 – Methods of Ketamine Delivery
2:15:40 – Contraindicators
2:18:06 – Clinical Research
2:21:59 – Cost

To learn more, go to onecommune.com/rewire to sign up for free for the first 4 days of Dr. Dave Rabin’s new Commune course Rewire Your Brain.

This podcast is supported by:

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Thrive Market
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Commune with Jeff Krasno

447. Unlocking the Psychedelic Puzzle: Serotonin, Ketamine, and the Future of Mental Health with Dr. Dave Rabin, PhD

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

Deep dives

The Importance of Safety in Neurocatalytic Therapy

Understanding Neuroplasticity and its Role in Mental Illness

The Misconception of Serotonin and Mental Illness

Addressing Mental Illness Through Burst Activation and Safety

Understanding the Adaptive Mechanisms in Our Body

The Role of Safety in Learning and Neuroplasticity

Utilizing Safety and Control for Mental Well-being

The Power of Ketamine Therapy

The Potential of Ketamine for Mental Health

The Effects of Exposure Therapy on Neural Networks

Anxiety and Depression

Remember Everything You Learn from Podcasts