On Friday, Israel launched massive strikes in Iran, targeting nuclear sites and killing top military leaders in the largest single-day attack on the country since the 1980s. Iran has retaliated, launching ballistic missiles at Israeli cities and killing at least eight people. Meanwhile, the Trump administration is walking a tightrope as it tries to maintain its alliance with Israel and negotiate a nuclear deal with Iran.

How might the war escalate from here? And what does this mean for America’s relationships in the region?

Guest: Gregg Carlstom, Middle East Correspondent for The Economist.

Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.

Podcast production by Ethan Oberman, Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme, and Rob Gunther.

Learn more about your ad choices. Visit megaphone.fm/adchoices

What Next | The War Netanyahu Always Wanted