Scientist Explains The Powerful Role Of Nitric Oxide In Preventing Alzheimer’s Disease And How To Protect Our Brains With Nathan Bryan, PhD
May 29, 2024
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Dr. Nathan Bryan discusses the importance of nitric oxide in preventing Alzheimer's disease, the dangers of acid-reducing drugs, and the impact of diet on nitric oxide levels. The podcast explores the role of nitric oxide in preventing chronic diseases, the connection between oral health and systemic wellness, and optimizing health with personalized nutrition.
Nitric oxide is crucial for cardiovascular health by promoting vasodilation and blood flow improvement.
Restoring nitric oxide levels can help manage various diseases by addressing inflammation and oxidative stress.
Proton pump inhibitors can increase risks of Alzheimer's disease and heart attacks by causing nutrient deficiencies.
Factors like sugar consumption and mouthwash use can decrease nitric oxide production and impact overall health.
Oral dysbiosis can lead to hypertension, emphasizing the importance of oral hygiene and water quality.
Taking proactive steps like balanced diet and physical exercise can optimize health and support nitric oxide production.
Deep dives
The Crucial Role of Nitric Oxide in Cardiovascular Health
Nitric oxide plays a vital role in cardiovascular health as it is responsible for maintaining the normal structure and function of blood vessels. The loss of nitric oxide can lead to vascular diseases like cardiovascular disease, making it a crucial factor in preventing disease onset and progression.
The Four Hallmarks of Disease and Nitric Oxide's Role
The four common denominators of disease, including low blood flow, inflammation, oxidative stress, and immune dysfunction, are key factors that nitric oxide addresses. Nitric oxide dilates blood vessels, improves blood flow, reduces inflammation, prevents oxidative stress, and mitigates immune dysfunction, making it essential for managing various diseases.
Nitric Oxide's Impact on Healthspan and Disease Reversal
Nitric oxide is considered essential for healthspan and longevity, as it aids in reversing diseases like coronary disease and atherosclerosis. By restoring nitric oxide function in the body, it is possible to dilate blood vessels, reduce inflammation, and regress the progression of chronic diseases, highlighting its significance in disease management and prevention.
The Link Between Proton Pump Inhibitors and Alzheimer's Disease
Millions of people use proton pump inhibitors, which are linked to increased risks of Alzheimer's disease and heart attacks. Prolonged use of proton pump inhibitors can lead to nutrient deficiencies and harmful health effects, emphasizing the importance of understanding the risks associated with commonly prescribed medications.
Lifestyle Factors and Nitric Oxide Production
Factors like excess sugar consumption, sedentary lifestyles, and the use of mouthwash can negatively impact nitric oxide production in the body. Making dietary changes, increasing physical activity, and avoiding harmful substances like mouthwash can help restore nitric oxide levels and promote better overall health.
Diagnostic Tools and Treatment for Hypertension
Hypertension can be a symptom of oral dysbiosis, where disruptions in the oral microbiome can lead to high blood pressure. Measures like discontinuing mouthwash usage and investing in high-quality water filtration systems can help improve oral health and potentially normalize blood pressure. Additionally, understanding the role of nitric oxide in vasodilation and blood pressure regulation is crucial for managing hypertension effectively.
Preventive Measures for Health Optimization
Taking proactive steps to avoid common disruptors of nitric oxide production, such as adopting a balanced diet, engaging in regular physical exercise, and ensuring sufficient sunlight exposure, can help optimize overall health. By addressing factors like water quality, oral hygiene practices, and lifestyle habits, individuals can support nitric oxide production and reduce the risk of chronic diseases.
Importance of Water Quality and Oral Health
Water quality, oral hygiene, and toxic exposures can significantly impact nitric oxide production and overall health. Investing in high-quality water filtration systems and maintaining good oral hygiene practices by avoiding harmful substances like mouthwash are essential for preserving nitric oxide levels and supporting overall well-being.
Nitric Oxide's Role in Disease Prevention
Nitric oxide's multifaceted benefits in regulating blood flow, reducing inflammation, and supporting immune function make it a key player in disease prevention. By understanding the factors that affect nitric oxide production and taking steps to enhance its levels, individuals can promote better health outcomes and reduce the risk of chronic conditions.
The Importance of Nitric Oxide for Health
Nitric oxide plays a crucial role in our health as a signaling molecule and hormone. It is essential for maintaining proper circulation and cardiovascular health. Deficiency in nitric oxide can lead to various health issues, including erectile dysfunction, high blood pressure, metabolic diseases, exercise intolerance, and even cognitive decline. Restoring nitric oxide levels is foundational for overall well-being and can positively impact various aspects of health.
Lifestyle Habits to Boost Nitric Oxide Levels
In addition to addressing nitric oxide deficiency, adopting healthy lifestyle habits can help boost nitric oxide levels naturally. Incorporating dark green leafy vegetables into the diet is beneficial, as they provide essential nutrients that support nitric oxide production. Other lifestyle practices like stress management, regular physical activity, and avoiding harmful substances can also contribute to enhancing nitric oxide levels.
Role of Nitric Oxide Supplements
Supplements containing nitric oxide-releasing components can serve as an additional support to increase nitric oxide levels. These supplements can be beneficial in cases where dietary sources may not be sufficient or for those looking to optimize their nitric oxide production. Using nitric oxide supplements as an insurance policy on top of a healthy diet and lifestyle can help ensure adequate nitric oxide levels for optimal health.
Future of Nitric Oxide Therapy
Ongoing research and development in the field of nitric oxide therapy are focused on potential pharmaceutical interventions. These developments aim to create drug-based solutions that target nitric oxide deficiency in specific health conditions like ischemic heart disease, Alzheimer's, and wound healing. By addressing nitric oxide at a therapeutic level, these advancements could offer new treatment options to address underlying health issues.
Conclusion
Emphasizing the importance of nitric oxide for overall health, lifestyle modifications, dietary choices, and the potential use of supplements or future drug therapies can all play a role in optimizing nitric oxide levels. By understanding the significance of nitric oxide in maintaining essential bodily functions, individuals can take proactive steps to support their health and well-being.
Cardiovascular disease still ranks as the leading cause of death for both men and women. Surprisingly, half of those affected show no symptoms before an event. Low levels of nitric oxide—a molecule that promotes vasodilation and smooth blood flow—could be primarily responsible. By recognizing the signs of deficiency, we can raise our levels and lower our risk.
Today on The Dhru Purohit Show, Dhru sits down for round two with Dr. Nathan Bryan to discuss why nitric oxide is the holy grail of molecules for long-term health. Dr. Bryan shares the four hallmarks of disease, the consequences of antacid overuse, and the correlation between lower nitric oxide and the risk of Alzheimer’s disease. Dr. Bryan also explains which lifestyle factors can hinder and boost nitric oxide production, how to test your levels, and symptoms that signal a deficiency.
Dr. Nathan Bryan is a renowned biomedical researcher known for his groundbreaking work on nitric oxide (NO) biology. Dr. Bryan's research has significantly advanced our understanding of NO's critical roles in cardiovascular health, immune function, and neurobiology. Beyond academia, he advocates for public health, translating his research into practical solutions for improving human health.
In this episode, Dhru and Dr. Bryan dive into (audio version / Apple Subscriber version):
Nitric oxide as the holy grail molecule (00:00:02 / 00:00:02)
Four hallmarks of disease (1:01 / 1:01)
Antacid medications: lack of research and the consequences of extended use (4:41 / 4:41)
Lower nitric oxide and the risk of Alzheimer’s (14:00 / 10:45)
Lifestyle habits that contribute to Alzheimer’s and biomarkers to check (17:15 /13:01)
What is nitric oxide and its core role in our bodies (27:00 / 23:39)
Lifestyle factors that hinder nitric oxide production (33:00 / 28:22)
Nitric oxide and high blood pressure (46:00 / 41:04)
Filtering water in your home and oral dysbiosis (51:00 / 46:30)
Navigating antacid medication usage and tapering off (1:11:00 / 1:06:50)
Testing nitric oxide level production (1:15:00 / 1:10:06)
The role of stress on our nitric oxide levels (1:29:00 / 1:24:53)
Foods that support production and supplementation (1:32:00 / 1:27:10)
Final thoughts: (1:44:00 / 1:39:40)
Also mentioned in this episode:
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